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This issue of Frontiers presents
2018-11-02

This issue of “Frontiers” presents some Italian works in the field of architectural and archaeological conservation and of museography. In itself, this sphingosine issue underlines and enhances the increasing importance of a productive cultural exchange in this field between China and Italy, two cou
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br Conclusion br Introduction Giant cell
2018-11-02

Conclusion Introduction Giant cell tumors (GCTs) of the bone account for 5% of all primary bone tumors. A GCT usually arises in the metaphyseal region of the long bones (e.g., distal femur, proximal tibia, distal radius), but it is rare in the cranium. It most often occurs at the age of 30–40
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Under ROC curve analysis the cutoff
2018-11-02

Under ROC curve analysis, the cutoff value in fascia defect width/abdominal circumference ratio was 13.99% with high sensitivity and specificity (100% and 100%, respectively). All cases with fascia defect width/abdominal circumference ratio larger than 13.99% showed complications of different extent
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C reactive protein is an acute phase protein produced
2018-11-02

C-reactive protein is an acute-phase protein produced by hepatocytes on stimulation by IL-6, which indicates a strong correlation between CRP and IL-6. IL-6 production is stimulated by IL-1b. Both IL-1b and IL-6 stimulate the production of IL-1-α, an anti-inflammatory cytokine that antagonizes IL-1
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A limitation of the study is the potential bias of
2018-11-02

A limitation of the study is the potential bias of the IV approach of administration. The proximity of the tail vein to the anal sphincter may suggest that MSCs could be trapped during their systemic course. Ours was an initial study and a longer time course of recovery is underway with different do
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Although in previous studies by Soldner et al
2018-11-02

Although in previous studies by Soldner et al. (2011) and Ding et al. (2013), an initial FACS-based enrichment step of TALEN-expressing norepinephrine bitartrate prior to subsequent PCR-based screening of this enriched cell population had to be included, both groups provided initial evidence that t
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How ABR participates in the control of mitotic fidelity rema
2018-11-02

How ABR participates in the control of mitotic fidelity remains an open question. Taking into consideration that ABR action is correlated with a cellular adhesive state, the present study suggests an unrecognized link between cell-cell contact and mitotic fidelity. In general, most types of non-tran
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Besides their direct effect on cartilage ASCs might act on
2018-11-02

Besides their direct effect on cartilage, ASCs might act on the other joint tissues as synovial membrane, ligaments, meniscus and subchondral bone that are also altered in OA. Although OA is not considered an inflammatory disease, pro-inflammatory cytokines, namely IL-1β and TNF-α, are secreted by O
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br Material and methods br Results br Discussion Aging assoc
2018-11-02

Material and methods Results Discussion Aging-associated phenotype change in hBMSCs is one of the most important considerations in furthering the advancement of cell-based therapy and is a subject of numerous studies and reviews (Baker et al., 2015; Bara et al., 2014). In regard to the in v
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ampa receptors The following is the supplementary data relat
2018-11-02

The following is the supplementary data related to this article. Authors\' contributions O.F. contributed to prepare experimental design, performed Ca measurements, helped with data and statistical analysis, immunocytochemistry, confocal imaging, and contributed in manuscript writing. Disclos
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Interestingly in contrast to the
2018-11-02

Interestingly, in contrast to the common roles of SNAI-1 and 2 in repressing E-cadherin mediated EMT, SNAI-1 is the only SNAI factor that is expressed in endoderm and Hep cells, and that instructs positively hepatic cell fate. The unique function of SNAI-1 compared to SNAI-2 was also noted during th
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In conclusion an MLR assay using hiPSC NS
2018-11-02

In conclusion, an MLR assay using hiPSC-NS/PCs revealed no significant differences between the HLA-matched and mismatched settings. The low antigen-presenting function and immunosuppressive effects of hiPSC-NS/PCs resulted in decreased immune reactions, even in the allogeneic HLA-mismatched NS/PC-PB
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We used immunohistochemistry to measure the expression of
2018-11-02

We used immunohistochemistry to measure the expression of RUNX2, SP7, and GFP in the induced 2.3 kb Col1a1-GFP mESCs. RUNX2, SP7, and the 2.3 kb Col1a1-GFP were highly expressed in the induced nicotinic receptor agonist on day 19. RUNX2 and SP7 were colocalized in nuclei, and 2.3 kb Col1a1-GFP was
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Mass spectrometry MS based proteomics is a
2018-11-02

Mass spectrometry (MS)-based proteomics is a powerful approach for the comparative analysis of protein Limitations between cell populations. Global approaches have been used to define the MSC proteome (Delorme et al., 2008; Mareddy et al., 2009; Mindaye et al., 2013a, 2013b) and to track the change
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Noticeably the redistribution of protein from the cytoplasm
2018-11-02

Noticeably, the redistribution of protein from the cytoplasm to the nucleus was observed in many regulatory molecules, such as nuclear factor κB (Haddad, 2009) and AKT (Xuan et al., 2006). We thus speculated that the increased nuclear MIF in hypoxic tumors may interact with the transcription factors
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